Steroid free cream helps clear up scaly skin of psoriasis



Biologics for Psoriasis: Big Results or Scary Side Effects?

Sign Up for Our Living with Psoriasis Newsletter

Thanks for signing up!

Like an uncaged lion, my psoriasis is roaring back all over my body. If I had any questions as to the severity of my psoriasis, then tapering and stopping Neoral (cyclosporine) over the past two months cleared those up. I expected my condition to get worse. But not this fast or widespread. Here we go again.

Appointment after appointment, my dermatologist suggested holding off on Stelara. She felt unsure about the safety profile over the long term. With little personal experience prescribing it, I would be one of her first patients to start the therapy. All that changed two weeks ago when she told me she felt more comfortable giving it to me and asked if I wanted to try it. Could it tame the lion of psoriasis without the kidney concerns that Neoral brings? Would it bring new, even potentially scarier, side effects?

I read an article in the Detroit Free Press called “Psoriasis drug promises big results, but price and side effects temper enthusiasm.” The article highlights the promise and risks of using a class of injectable medications called biologics. I’ve tried a few of them over the years such as Amevive, Humira, and Enbrel (etanercept, what I’m currently taking). One doctor quoted in the article encapsulates the dilemma I face with these medications:

"The hoopla is that with these new drugs a person can get a shot that takes care of their psoriasis for three months; that's a good thing," said Dr. Thomas Anderson, medical director of the University of Michigan Day Treatment Center, one of 12 in the country that provides outpatient care for the skin disease.

"But as time goes on, these drugs may not be as effective in some patients," Anderson said. "If you get an infection while you are on one of those drugs, your body may not be as capable of getting rid of it."

Sure enough, I can tell that Enbrel has lost effectiveness after three to four years of continual use. Stelara is an option now, but it is a newer drug with a relatively shorter track record and safety profile. The article also speaks specifically to my safety concerns:

Safety warnings listed on the labels for the drugs mention the chance of serious infections, TB and cancer, and recommend that people tell doctors before filling a prescription if they have diabetes, are scheduled for major surgery, are pregnant, have heart failure, cancer or nervous system disorders, among other chronic problems.

Doctors at U-M and Detroit's Henry Ford Hospital, among others, tell patients that biologics aren't often the best first choice because of the problems associated with them.

"We almost always try other things first," said Dr. Iltefat Hamzavi, a Canton dermatologist and Henry Ford Health System physician. Hamzavi limits the drugs to patients with psoriasis over 10% or more of their body, or people with arthritic psoriasis, a painful joint problem. Psoriatic arthritis usually appears between the ages of 30 and 50 and is believed to be triggered by genes, the immune system and environmental factors, according to the National Psoriasis Foundation.

The article goes on to discuss other treatments, cost, and an upcoming webcast sponsored by the on “Systemics and Biologics: Risks and Rewards,” if you want to check those out.

The “try other things first” mentality is exactly where I’m at today. I am finding comfort in knowing my friends are praying for me. I am looking at less intrusive therapies such as coal tar and sunlight with a renewed interest in experimenting with diet, exercise, and relaxation. But the option of taking a shot every few months still tempts me.

What do you think about taking biologics, especially the cost and potential risks and rewards? What has been your experience using them?

Last Updated:6/24/2011
Important:The views and opinions expressed in this article are those of the author and not Everyday Health.
Any opinions, advice, statements, services, advertisements, offers or other information or content expressed or made available through the Sites by third parties, including information providers, are those of the respective authors or distributors and not Everyday Health. Neither Everyday Health, its Licensors nor any third-party content providers guarantee the accuracy, completeness or usefulness of any content. Furthermore, neither Everyday Health nor its Licensors endorse or are responsible for the accuracy and reliability of any opinion, advice or statement made on any of the Sites or Services by anyone other than an authorized Everyday Health or Licensor representative while acting in his/her official capacity. You may be exposed through the Sites or Services to content that violates our policies, is sexually explicit or is otherwise offensive. You access the Sites and Services at your own risk. We take no responsibility for your exposure to third party content on the Sites or the Services. Everyday Health and its Licensors do not assume, and expressly disclaim, any obligation to obtain and include any information other than that provided to it by its third party sources. It should be understood that we do not advocate the use of any product or procedure described in the Sites or through the Services, nor are we responsible for misuse of a product or procedure due to typographical error.





Video: What Alcohol Can Do To Your Liver

Biologics for Psoriasis: Big Results or Scary Side Effects
Biologics for Psoriasis: Big Results or Scary Side Effects images

2019 year
2019 year - Biologics for Psoriasis: Big Results or Scary Side Effects pictures

Biologics for Psoriasis: Big Results or Scary Side Effects advise
Biologics for Psoriasis: Big Results or Scary Side Effects advise photo

Biologics for Psoriasis: Big Results or Scary Side Effects picture
Biologics for Psoriasis: Big Results or Scary Side Effects pics

Biologics for Psoriasis: Big Results or Scary Side Effects Biologics for Psoriasis: Big Results or Scary Side Effects new foto
Biologics for Psoriasis: Big Results or Scary Side Effects new foto

foto Biologics for Psoriasis: Big Results or Scary Side Effects
picture Biologics for Psoriasis: Big Results or Scary Side Effects

Watch Biologics for Psoriasis: Big Results or Scary Side Effects video
Watch Biologics for Psoriasis: Big Results or Scary Side Effects video

Forum on this topic: Biologics for Psoriasis: Big Results or Scary , biologics-for-psoriasis-big-results-or-scary/
Discussion on this topic: Biologics for Psoriasis: Big Results or Scary , biologics-for-psoriasis-big-results-or-scary/ , biologics-for-psoriasis-big-results-or-scary/

Related News


Two Bumps, One Baby: Check Out This Hilariously Honest Pregnancy Reveal
5 Genius Ways to Dress Up Without Overheating This Summer
How to Diagnose Eye Problems in Boston Terriers
Disneyland is selling alcohol for the first time in a Star Wars bar
How to Avoid Paying York University Parking Tickets
How to Lose Weight in Two Weeks
Top 7 Power Yoga Videos
I Decided to Laser my Fat
How to Buy a Japanese Stock
25 Restaurant Meals Under 500 Calories



Date: 12.12.2018, 16:11 / Views: 64361